Nobel prize for the development of asymmetric organocatalysis

Congratulations to Benjamin List and David W.C. MacMillan who are joining the most honourable team of Nobel Prize for Chemistry recipients!

The duo received the Nobel Prize 2021 in Chemistry for the development of asymmetric organocatalysis. Asymmetric organocatalysis (or enantioselective synthesis) is a key process in modern chemistry and is particularly important in the field of pharmaceuticals, as the different enantiomers or diastereomers of a molecule often have different biological activity.[1]

The differentiation of these enantiomers is best done by diffraction in determining the absolute configuration, e.g. with X-rays on single crystals of 50 to 500 µm or with electron diffraction on  crystallites as small as 50 to 500 nm! Electron Diffraction is gaining momentum in science and industry. The application of ED for performing nanocrystallography is a disruptive innovation that is opening up fascinating new perspectives particularly for organic compounds required in the fields of chemical and pharmaceutical  research.

For more information on enantiomers and absolute configuration with electron diffraction, watch our webinar with Lukas Palatinus here



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ELDICO Scientific AG (The Electron Diffraction Company) is a Swiss technology and service company founded in 2019 and based in the Switzerland Innovation Park Innovaare at the Paul Scherrer Institute (PSI), a world-leading research institute for natural sciences and engineering. ELDICO develops, manufactures and commercializes electron diffractometers , i.e. novel analytical instruments for electron based crystallography, enabling to investigate nano-crystalline samples. ELDICO will launch the first instrument specifically designed for nano-crystallographic investigations. Proof-of-concept was achieved in 2018 (ETH Zurich, C-CINA Basel) as part of a Nano-Argovia project of the Swiss Nanoscience Institute (SNI). It was published in 2018 and awarded Top 5 "Breakthrough of the Year 2018" by the leading science magazine SCIENCE. In 2020 among other public recognitions on Swiss and EU level, ELDICO took 2nd place in the prestigious Pioneer Prize awarded by Technopark Zurich and the Zürcher Kantonalbank (ZKB). ELDICO’s clients are industrial and academic researchers in large and fast growing industries such as the pharmaceutical industry, the electromobility, and the advanced materials / MOF sector. The company partners with leading engineering companies and component suppliers among Dectris, Excillum and SmarAct to deliver superior performance.